木戸秋研究室

A. 学術論文情報（Papers）

1. Avoiding tensional equilibrium in cells migrating on a matrix with cell-scale stiffness-heterogeneity

H. Ebata and S. Kidoaki*,
https://www.biorxiv.org/content/10.1101/2020.10.15.342006v1

2. Designing elastic modulus of cell culture substrate to regulate YAP and RUNX2 localization for controlling differentiation of human mesenchymal stem cells

M. Yamazaki, S. Kidoaki, H. Fujie, H. Miyoshi*,
Anal. Sci. in press.
 

3. High axial and lateral resolution on self-assembled gold nanoparticle metasurfaces for live-cell imaging

S. Masuda,T. Kuboki, S. Kidoaki, S-T. Lee, S. Ryuzaki, K. Okamoto, Y. Arima, K. Tamada*,
ACS Appl. Nano Mater. doi: 10.1021/acsanm.0c02300
https://pubs.acs.org/doi/abs/10.1021/acsanm.0c02300

4. Why epithelial cells collectively move against a traveling signal wave

T. Fukuyama, H. Ebata, Y. Kondo, S. Kidoaki, K. Aoki, Y. T. Maeda*, 
https://arxiv.org/abs/2008.12955

5. Hierarchical development of motile polarity in durotactic cells just crossing an elasticity boundary

T. Kuboki, H. Ebata, T. Matsuda, Y. Arai, T. Nagai, S. Kidoaki*, 
Cell Struct. Funct., 45, 33-43, 2020. 
https://doi.org/10.1247/csf.19040

6. Mechanisms of endothelial cell coverage by pericytes: computational modelling of cell wrapping and in vitro experiments

K. Sugihara, S. Sasaki, A. Uemura, S. Kidoaki, and T. Miura*, 
J. R. Soc. Interf., 17, 20190739, 2020. 
https://doi.org/10.1098/rsif.2019.0739

7. Stiffness-optimized drug-loaded matrix for selective capture and elimination of cancer cells,

D. Huang and S. Kidoaki*, 
J. Drug Deliv. Sci. Technol., 55, 101414, 2020. 
https://doi.org/10.1016/j.jddst.2019.101414

8. Characterization of 3D matrix conditions for cancer cell migration with elasticity/porosity-independent tunable microfiber gels

D. Huang, Y. Nakamura, A. Ogata, S. Kidoaki*,
Polymer J., 52, 333-344, 2020. 
https://doi.org/10.1038/s41428-019-0283-3

9. General cellular durotaxis induced with cell-scale heterogeneity of matrix-elasticity

H. Ebata, K. Moriyama, T. Kuboki, S. Kidoaki*, 
Biomaterials, 203, 119647, 2020. 」https://doi.org/10.1016/j.biomaterials.2019.119647

10. Precise design of microwrinkles through the independent regulation of elasticity in the surface and bulk of soft hydrogels

S. Sasaki and S. Kidoaki*, 
Polymer J., 52, 515-522, 2020. 
https://doi.org/10.1038/s41428-019-0299-8

11. Multimeric conformation of type III intermediate filaments but not the filamentous conformation exhibits high affinity to lipid bilayers

B. Hwang, H. Ise *
Genes Cells, 2020, 25, 413-426. 
https://doi: 10.1111/gtc.12768

12. Development of a Gene Delivery System of Oligonucleotides for Fibroses by Targeting Cell-Surface Vimentin-Expressing Cells with N-Acetylglucosamine-Bearing Polymer-Conjugated Polyethyleneimine. I. Song, H. Ise*

Polymers (Basel), 2020, 12, 1508. 
https://doi: 10.3390/polym12071508

B. 総説・解説（Reviews）・著書(Books)

1. 機械工学年鑑2020 -機械工学の最新動向-：バイオマテリアル,

木戸秋 悟, 
日本機械学会 
https://www.jsme.or.jp/kikainenkan2020/chap03/#a04

2.間葉系幹細胞の分化抑制培養力学場の設計,

木戸秋 悟,
曽我部正博編集 実験医学増刊号「疾患に挑むメカノバイオロジー」, 38, 1251-1255, 2020.

3. 微視的ヘテロ力学場を用いた治療効果増強幹細胞の培養技術,

木戸秋 悟,
医学のあゆみ, 医歯薬出版 276, 241-245, 2021.

4. 組織線維化に対する標的化とその標的化技術の開発

伊勢裕彦*
別冊BIO Clinica 慢性炎症と疾患、自己免疫疾患、編集主幹　高柳　広，2020, Vol.9, 102-106

C. 特許情報（Patents）

国内特許出願　3件

D. その他の活動（プレスリリース・新聞記事等・広報資料）

1. プラズモンメタ表面で「生きた細胞」内の分子の動きをナノの解像度で直接観る 

https://www.kyushu-u.ac.jp/ja/researches/view/514
日経産業新聞　NextTech2030「生きた細胞を超精密診断」
2020年11月6日（金曜日）掲載

2. 日本経済新聞　電子版（NextTech2030）「生きた細胞を超精密診断　がん早期発見、光学の限界突破」

2020/11/6付け　掲載

3. High Axial and Lateral Resolutions on Self-Assembled Gold Nanoparticle Metasurfaces for Live-Cell Imaging

著者名：Shihomi Masuda, Thasaneeya Kuboki, Satoru Kidoaki, Shi Ting Lee, Sou Ryuzaki, Koichi Okamoto, Yusuke Arima, and Kaoru Tamada*
掲載誌：ACS Applied Nano Materials
DOI：10.1021/acsanm.0c02300