日下部研究室

A. 学術論文情報（Papers）

1. A defect in purine nucleotide metabolism in the silkworm, Bombyx mori, causes a translucent larval integument and male infertility

Tsuguru Fujii, Kohei Kakino, Miyu Tanaka, Jae Man Lee, Takahiro Kusakabe, Yutaka Banno
Insect Biochemistry and Molecular Biology, 2020, 126, 103458
https://www.sciencedirect.com/science/article/pii/S0965174820301478?via%3Dihub

2. Using Eukaryotic Expression Systems to Generate Human α1, 3-Fucosyltransferases That Effectively Create Selectin-Binding Glycans on Stem Cells

Asma S Al-Amoodi, Kosuke Sakashita, Amal J Ali, Ruoyu Zhou, Jae Man Lee, Muhammad Tehseen, Mo Li, Juan Carlos I Belmonte, Takahiro Kusakabe, Jasmeen S Merzaban
Biochemistry, 2020, 59, 3757-3771
https://doi.org/10.1021/acs.biochem.0c00523

3. Efficient production of recombinant SARS-CoV-2 spike protein using the baculovirus-silkworm system

Ryosuke Fujita, Masato Hino, Takeru Ebihara, Takumi Nagasato, Akitsu Masuda, Jae Man Lee, Tsuguru Fujii, Hiroaki Mon, Kohei Kakino, Ryo Nagai, Miyu Tanaka, Yoshino Tonooka, Takato Moriyama, Takahiro Kusakabe
Biochemical and Biophysical Research Communications, 2020, 529, 257-262
https://doi.org/10.1016/j.bbrc.2020.06.020

4. Efficient production of recombinant T7 endonuclease I using silkworm-baculovirus expression vector system

Kohei Kakino, Akitsu Masuda, Masato Hino, Takeru Ebihara, Jian Xu, Hiroaki Mon, Ryosuke Fujita, Tsuguru Fujii, Takahiro Kusakabe, Jae Man Lee
Journal of Asia-Pacific Entomology, 2020, 23, 694-700
https://doi.org/10.1016/j.aspen.2020.05.001

5. Functional binding of E-selectin to its ligands is enhanced by structural features beyond its lectin domain

Fajr A Aleisa, Kosuke Sakashita, Jae Man Lee, Dina B AbuSamra, Bader Al Alwan, Shuho Nozue, Muhammad Tehseen, Samir M Hamdan, Satoshi Habuchi, Takahiro Kusakabe, Jasmeen S Merzaban
Journal of Biological Chemistry, 2020, 295, 3719-3733
https://doi.org/10.1074/jbc.RA119.010910

6. Mild inactivation and inhibition of phenoloxidase in silkworm serum for xeno-free culture of insect cells

Masato Hino, Noriko Karasaki, Tsuneyuki Tatsuke, Daisuke Morokuma, Akitsu Masuda, Hiroaki Mon, Jae Man Lee, Takahiro Kusakabe
Journal of Insect Biotechnology and Sericology, 2020, 89, 1-16
https://doi.org/10.11416/jibs.89.1_009

7. Optimal silkworm larva host for high-level production of Mus musculus IL-4 using a baculovirus expression vector system

M. Kobayashi, J. Xu, A. Masuda, M. Hino, N. Fujimoto, K. Minamihata, N. Kamiya, H. Mon, H. Iida, M. Takahashi, T. Kusakabe, J.-M. Lee
Journal of Asia-Pacific Entomology, 2020, 23, 268-273.
https://doi.org/10.1016/j.aspen.2019.12.014
[未来化セ・バイオ 神谷研との共同研究成果]

8. Clomipramine suppresses ACE2-mediated SARS-CoV-2 entry

Y. Kato, S. Yamada, K. Nishiyama, A. Satsuka, S. Re, D. Tomokiyo, J.-M. Lee, T. Tanaka, A. Nishimura, K. Yonemitsu, H. Asakura, Y. Ibuki, Y. Imai, N. Kamiya, K. Mizuguchi, T. Kusakabe, Y. Kanda*, M. Nishida*
bioRxiv preprint doi: https://doi.org/10.1101/2021.03.13.435221
[薬学研究院 西田研・未来化セ・バイオ 神谷研との共同研究成果]

B. 総説・解説（Reviews）・著書(Books)

1. 新型コロナウイルス（SARS-CoV-2）の細胞内侵入を防ぐ既存薬を同定 －新しいCOVID-19治療薬の開発へ！－

九州大学プレスリリース（2021/3/17）
https://www.kyushu-u.ac.jp/ja/researches/view/578
https://www.kyushu-u.ac.jp/f/42927/21_03_17.pdf
[薬学研究院 西田研・未来化セ・バイオ 神谷研との共同研究成果]

C. 特許情報（Patents）

該当なし

D. その他の活動（プレスリリース・新聞記事等・広報資料）

該当なし